Chemopreventive and anti-breast cancer activity of compounds isolated from leaves of Abrus precatorius L.
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منابع مشابه
Anticonvulsant Activity of Ethanolic Extract of Abrus Precatorius Leaves
Abrus precatorius which is commonly called as Indian licorice has been used for many centuries by traditional healers of Tanzania for the treatment of convulsions. The present work has been carried out to evaluate the anticonvulsant activity of the ethanolic extract (EE) of A. precatorius leaves against Pentylenetetrazole (PTZ), Picrotoxin and Maximal electroshock (MES) induced convulsions at t...
متن کاملAbrus precatorius Linn leaves in wistar rats
Abrus precatorius leaves have been used in traditional medicine for the treatment of a variety of diseases including cough, malaria and infertility in women. It has also been shown to have various useful pharmacological effects. In this study, oral acute toxicity of the aqueous, 70% methanol, Petroleum ether and Acetone extracts were investigated. The graphical method of Miller and Tainter was ...
متن کاملImmunopotentiating activity of abrin, a lectin from Abrus precatorius Linn.
A non-toxic dose of abrin, (1.25 microg/kg body wt) consecutively for five days in normal mice stimulated specific humoral responses. A noticeable increase was observed in total leucocyte count, lymphocytosis, weights of spleen and thymus, circulating antibody titre, antibody forming cells, bone marrow cellularity and alpha-esterase positive bone marrow cells. The results suggest that abrin can...
متن کاملAntitrypanosomal isoflavan quinones from Abrus precatorius.
Human African trypanosomiasis is a neglected tropical disease in sub Saharan Africa that is fatal if left untreated. In a search for new natural products with antitrypanosomal activity, we recently identified abruquinones B and I from Abrus precatorius as potent in vitro trypanocidal compounds with high selectivity indices. To obtain sufficient compound for in vivo efficacy tests in mice, a sec...
متن کاملAntioxidant Properties and Effect of Abrus precatorius Leaves Extract on Haematological and Biochemical Parameters in Rats
Background Abrus precatorius (A. precatorius) is a herbal remedy commonly used in traditional medicine. We investigated the phytochemical, antioxidant, toxic properties, and safety of A. precatorius leaves in rats. Methods Phytochemical studies were conducted using standard procedures. The antioxidant properties were studied using the reducing power and 2, 2′- diphenyl-1-picrylhydrazyl (DPPH...
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ژورنال
عنوان ژورنال: 3 Biotech
سال: 2018
ISSN: 2190-572X,2190-5738
DOI: 10.1007/s13205-018-1395-8